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Cell surface markers (CSM) are proteins, glycoproteins, or carbohydrates present on the membrane of cells. They play crucial roles in cellular identification, signaling, and interactions with the environment. These markers help differentiate various cell type such as immune cells, stem cells, and cancer cells, making them essential in both basic research and clinical application.
AnyGenes provide cutting-edge qPCR arrays designed to facilitate the high-throughput analysis of cell surface markers across different species, including human, mouse, rat and pig. These arrays are highly customizable, offering researchers reliable tools for studying complex cellular processes such as immune response, stem cell differentiation and cancer progression.
Differentiation of T-cell subsets and their respective cell surface marker.
Surface markers are widely used in various research areas. Some notable markers include:
CSM play a key role in cellular communication by regulating important signaling pathways that control growth, differentiation and immune response. Markers such as CD4 and CD8 are involved in T-cell activation, while EGFR and PD-1/PD-L1 influence cancer progression and immune evasion.
Signaling pathways like EGFR, NOTCH and Wnt rely on specific surface markers to trigger cellular responses. These pathways are critical for research in cancer, immunology and regenerative medicine.
Surface markers are pivotal in the field of immunotherapy, where they serve as targets for therapeutic agents designed to enhance the immune response against tumors. By identifying specific markers, such as PD-1 and CTLA-4, researchers can develop checkpoint inhibitors that block these pathways, allowing T cells to better attack cancer cells.
Recent advancements in technologies for analyzing CSM have significantly enhanced cancer diagnosis and monitoring. Techniques such as flow cytometry, mass cytometry, and single cell RNA sequencing provide detailed insights into the expression and functionality of surface markers on tumor cells. These technologies enable researchers to identify specific markers that indicate tumor types, stages and potential responses to therapies.
Customize your own signaling pathways (SignArrays®) with the factors of your choice!
Simply download and complete our Personalized SignArrays® information file
and send it at
contact@anygenes.com
to get started on your project.
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Cell Surface Markers |
CSM1H1 |
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Cell Surface Markers |
CSM1M1 |
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Cell Surface Markers |
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Cell Surface Markers |
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