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Innate and Adaptive Immunity  Innate & Adaptive Immune Response

The immune system has two important branches, Innate and adaptive immunity which plays essential role for health and initiation and progression of chronic inflammatory diseases (1).
Innate-and-adaptive -immunity

Innate-adaptive immunity interplay in immune response (1)

The recognized characteristic in the innate and adaptive immune system is ''Memory ''' which enhances host survival upon reinfection (2).

Innate and Adaptive Immunity Signaling Pathways play critical roles in health and the initiation and progression of chronic inflammatory diseases Immune Response and diseases

Studies have proven that dysfunction of innate and adaptive immune response is considered to be a key step in the initiation and maintenance of autoimmune diseases (3), atherosclerosis (4), COVID-19 (5), Parkinson's disease …(6).
(1) Sun L, et al. Innate-adaptive immunity interplay and redox regulation in immune response. Redox Biol. (2020);37:101759. 
(2) Netea MG, et al. Innate and Adaptive Immune Memory: an Evolutionary Continuum in the Host's Response to Pathogens. Cell Host Microbe. (2019);25(1):13-26.
(3) Zhang Y, et al. NLRP3 Inflammasome: Checkpoint Connecting Innate and Adaptive Immunity in Autoimmune Diseases. Front Immunol. (2021);12:732933.
(4) Roy P, et al. How the immune system shapes atherosclerosis: roles of innate and adaptive immunity. Nat Rev Immunol. (2022);22(4):251-265.
(5) Carsetti R, et al.  Different Innate and Adaptive Immune Responses to SARS-CoV-2 Infection of Asymptomatic, Mild, and Severe Cases. Front Immunol. (2020);11:610300.
(6) Schonhoff AM, et al. Innate and adaptive immune responses in Parkinson's disease. Prog Brain Res. (2020);252:169-216
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