All-in-one solution SignArrays system to explore your favorite Signaling Pathways

qPCR Validated Primers Sets to analyse any genes for any species

cDNA Preamplification SpeAmpn reagents to analyse until 4 signaling pathways from only 5ng of RNA.

qPCR SignArrays Signaling Pathways

YOUR FAVOURITE SIGNALING PATHWAYS!
SPEND LESS MONEY AND GET MORE RESULTS!

You can find any Signaling Pathways for Human, Mouse,
Rat and any species at very competitive prices

ALL IN ONE SOLUTION SIGNARRAYS® SYSTEM

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diapoepigen

Epigenetic regulation ( Newsletter 03/17 )

How epigenetic factors can modify the cell
fate and be actively involved in carcinogenesis.

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qPCR Validated Primer sets

Analyse any genes or panel of genes for any species at very competitive prices

- Experimentally validated
- Totally customizable
- Perfect for many applications

Discover now our Validated Primer Sets !

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cDNA Preamplification SpeAmpn kit

NEW !

Analyse more Signaling Pathways from few biological
material (5ng) thanks to our cDNA preamplification SpeAmpn Kits!

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Analyse your microbiota profile

Analyse your microbiota profile at very competitive
prices with our new range of experimentally validated
microbiota assays and SignArrays!

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News

1- FORUM LABO PARIS 28-30 MARCH 2023

Please join us at our booth #H105, hall H, to learn more about AnyGenes's products and molecular services

2- 7th Drug Discovery Summit, 2022-Madrid

AnyGenes will participate to the 7th Drug Discovery Summit, 2022-Madrid. Dr NAIMI, will give a talk on the importance of signaling pathways and biomarkers in the process of drug development, by using AnyGenes molecular platform

3- Importation of biological samples

AnyGenes obtained from The Ministry of Agricultural the authorisation to import biological samples from outside the European Union

4- Distribution agreement with Hölzel Diagnostika

We welcome Hölzel Diagnostika Handels GmbH as new distributor of AnyGenes products and services in Germany, Austria and Switzerland

5- BIO-Europe Spring 2020

AnyGenes will be present at BIO-Europe Spring 2020

6- AnyGenes products and services in JAPAN

We are proud to have signed an agreement with the company Funakoshi, Co, Ltd, for the distribution of AnyGenes products and services in JAPAN

7- BIOFIT 2018, LILLE, 4-5 December

AnyGenes team will be present at BioFIT Event 2018 at Lille, FRANCE

8- Specific Pre-amplification kit

You have small quantity of biological sample but many signaling pathways to explore? AnyGenes® team is proud to help you with our new range of cDNA pre-amplification SpeAmpⁿ system to perform high-throughput analysis with very small amounts of biological material (5 ng RNA) or few cells.

9- MEDICA 2017/ Dûsseldorf, GERMANY, 13-16 NOV

AnyGenes® team was present at MEDICA 2017, the key world forum for medicine. AnyGenes® stays informed of all the news, innovative projects, latest technologies and issues in medical fields in order to offer you innovative products and tools.

10- BioJapan/ Regenerative Medicine Japan 2016

AnyGenes® has been selected by the EU-Japan centre, for BtoB meetings at Osaka from 9-11 October, and to present its products (SignArrays®) and its multi-biomarkers clinical tests at BioJapan 2016, October 12-14, Yokohama, JAPAN.

11- Chinese Medicine Conference 2016

Dr Ju Liya has held a conference at the 2nd World Forum on Astragalus membranaceus, 10 June 2016 at Beijing CHINA. Dr Ju Liya had talked about interesting results from in vitro analysis of compounds from chinese medicine by using AnyGenes® molecular platform.

12- Products

Discover now our various signaling pathways (SignArrays®) and Highly sensitive and specific assay kits for specific gene quantification by real time qPCR array.

Cell signaling and biomarkers profiler

Since more than 15 years, AnyGenes has developed a large catalog of molecular biology reagents and assays dedicated to gene expression, cell signaling and biomarkers profiling.

All the AnyGenes products have been developed, optimized and experimentally validated to guarantee high performance and highly accurate results.

Thanks to its own high-throughput molecular platform, AnyGenes also provides full services, from cell culture to biomarkers identification and validation with high-throughput data analysis, to support your research and drug development projects.

Cell signaling and biomarkers assays and services

Discover now our whole range of complete solutions to boost your projects.

Signaling Pathways

cell signaling and biomarkers _Improve your qPCR results with our Perfect Master Mixes.

qPCR Master Mixes

cell signaling and biomarkers _ You can now analyse until 4 signaling pathways from only 5ng of RNA using the cDNA Preamplification SpeAmpn kit.

Pre-Amplification Kits NEW!

Validated Primer Sets

Biomarker Platform Services

Microbiota Assays NEW!

cell signaling and biomarkers _ MycoDiag assays ensure a fast and reliable screening of your cell culture supernatants for Mycoplasma contamination by qPCR or PCR .

Mycoplasma Detection Assays

LncRNA qPCR assays

Some of scientific publications with our products

- Chen W et al. CircRNA circPTK2 Might Suppress Cancer Cell Invasion and Migration of Glioblastoma by Inhibiting miR-23a Maturation. Neuropsychiatr Dis Treat. (2021) 17: 2767-2774

- Reger de Moura C et al. CD147 Promotes Tumor Lymphangiogenesis in Melanoma via PROX-1. Cancers (2021) 13(19): 4859

- Linillos-Pradillo B et al. Determination of SARS-CoV-2 RNA in different particulate matter size fractions of outdoor air samples in Madrid during the lockdown. Environ Res (2021) 195:110863

- Garcia P et al. Disruption of NIPBL/Scc2 in Cornelia de Lange Syndrome provokes cohesin genome-wide redistribution with an impact in the transcriptome. Nature Communications (2021) 12(1): 4551

- Vasilopoulou F et al. Microarray Analysis Revealed Inflammatory Transcriptomic Changes after LSL60101 Treatment in 5XFAD Mice Model. Genes (2021) 12(9): 1315-1327

- Haijun Wan H et al. CircRNA CircRIMS is Overexpressed in Esophageal Squamous Cell Carcinoma and Downregulate miR-613 Through Methylation to Increase Cell Proliferation. Cancer Manag Res. (2021) 13: 4587-4595

- Ribó P et al. Mutation in KARS: A novel mechanism for severe anaphylaxis. J Allergy Clin Immunol. (2021) 147(5): 1855-1864

- Bouchet M et al. ERRα Expression in Bone Metastases Leads to an Exacerbated Antitumor Immune Response. Cancer Res. (2020) 80(13): 2914-2926

- Tétu P et al. FGF2 Induces Resistance to Nilotinib through MAPK Pathway Activation in KIT Mutated Melanoma. Cancers (2020) 12(5): 1062

- Moreno-Rubio J et al. Clinical-pathological and molecular characterization of long-term survivors with advanced non-small cell lung cancer. Cancer Biol Med. (2020) 17(2):444-457

- Tong C et al. Repurposing loperamide to overcome gefitinib resistance by triggering apoptosis independent of autophagy induction in KRAS mutant NSCLC cells. Cancer Treat Res Commun. (2020) 25: 100229

- Ataam AJ et al. Targeted Angiogenesis Gene Expression Profiling of Patients with Chronic Thromboembolic Pulmonary Hypertension. J. Heart Lung Transplant. (2020) 39(4): S31

- Martínez-García MA et al. TLR2 and TLR4 Surface and Gene Expression in White Blood Cells after Fasting and Oral Glucose, Lipid and Protein Challenges: Influence of Obesity and Sex Hormones. Biomolecules (2020) 10(1): 111

- Reger de Moura C et al. Intermittent Versus Continuous Dosing of MAPK Inhibitors in the Treatment of BRAF-Mutated Melanoma. Transl Oncol. (2019) 13(2): 275-286

- Louveau B et al. Baseline Genomic Features in BRAFV600-Mutated Metastatic Melanoma Patients Treated with BRAF Inhibitor + MEK Inhibitor in Routine Care. Cancers (2019) 11(8): E1203

- Dupain C et al. Newly identified LMO3-BORCS5 fusion oncogene in Ewing sarcoma at relapse is a driver of tumor progression. Oncogene (2019) 38(47): 7200-7215

- Reger de Moura C et al. Discoidin Domain Receptors: A promising target in melanoma. Pigment Cell Melanoma Res. (2019) 32(5): 697-707

- Louveau B et al. A targeted genomic alteration analysis predicts survival of melanoma patients under BRAF inhibitors. Oncotarget (2019) 10(18): 1669-1687

- Félix AJ et al. Functional pharmacogenomics and toxicity of PolyPurine Reverse Hoogsteen hairpins directed against survivin in human cells. Biochem Pharmacol. (2018) 155:8-20

- Torres RJ & Puig JG. Aicar effect in early neuronal development. Nucleos Nucleot Nucl. (2018) 37(5): 261-272

- Delyon J et al. STAT3 Mediates Nilotinib Response in KIT-Altered Melanoma: A Phase II Multicenter Trial of the French Skin Cancer Network. J Invest Dermatol. (2018) 138(1): 58-67

- Mgrditchian T et al. Targeting autophagy inhibits melanoma growth by enhancing NK cells infiltration in a CCL5-dependent manner. Proc Natl Acad Sci. (2017) 114(44): 9271-9279

- Buart S et al. Transcriptional response to hypoxic stress in melanoma and prognostic potential of GBE1 and BNIP3. Oncotarget (2017) 8(65): 108786-108801

- Broséus J et al. VEGF121, is predictor for survival in activated B-cell-like diffuse large B-cell lymphoma and is related to an immune response gene signature conserved in cancers. Oncotarget (2017) 8(53): 90808-90824

- Delyon J et al. PDE4D promotes FAK-mediated cell invasion in BRAF-mutated melanoma. Oncogene (2017) 36(23): 3252-3262

- Doucet M et al. Quality Matters: 2016 Annual Conference of the National Infrastructures for Biobanking. Biopreserv Biobank (2017) 15(3): 270-276

- Delyon J et al. Validation of a preclinical model for assessment of drug efficacy in melanoma. Oncotarget (2016) 7(11): 13069-13081

- Xu-Dubois YC et al. Markers of endothelial to mesenchymal transition: evidence for antibody-endothelium interaction during antibody mediated rejection in kidney recipients. J Am Soc Nephrol. (2016) 27(1): 324-332

- Mourah S et al. Dramatic Transient Improvement of Metastatic BRAFV600E-Mutated Langerhans Cell Sarcoma under treatment with Dabrafenib. Blood (2015) 126(24): 2649-2652

- Delyon J et al. EMMPRIN regulates β1 integrin-mediated adhesion through Kindlin-3 in human melanoma cells. Exp Dermatol. (2015) 24(6): 443-448

- Khayati F et al. EMMPRIN/CD147 is a novel coreceptor of VEGFR-2 mediating its activation by VEGF. Oncotarget (2015) 6(12): 9766-9780

- Ranchoux B et al. Endothelial-to-mesenchymal transition in pulmonary hypertension. Circulation (2015) 131(11): 1006-1018

- Djaafri I et al. A novel tumor suppressor function of Kindlin-3 in solid cancer. Oncotarget (2014) 5(19): 8970-8985

- Milia-Argeiti E et al. EMMPRIN/CD147-encriched membrane vesicles released from malignant human testicular germ cells increase MMP production through tumor-stroma interaction. Biochim Biophys Acta (2014) 1840(8): 2581-2588

- Lescaille G et al. EMMPRIN/CD147 up-regulates urokinase-type plasminogen activator: implications in oral tumor progression. BMC Cancer (2012) 12(115): 1-9

- Milia-Argeiti E et al. Imbalance of MMP-2 and MMP-9 expression versus TIMP-1 and TIMP-2 reflects increased invasiveness of human testicular germ cell tumours. Int J Androl. (2012) 35(6): 835-844

- Abdelkarim M et al. Invading Basement Membrane Matrix Is Sufficient for MDA-MB-231 Breast Cancer Cells to Develop a Stable In Vivo Metastatic Phenotype. PLoS ONE (2011) 6(8): e23334.

- Huet E et al. EMMPRIN Modulates Epithelial Barrier Function through a MMP-Mediated Occludin Cleavage: Implications in Dry Eye Disease. Am J Pathol. (2011) 179(3): 1278-1286

- Moreau M et al. b-Catenin and NF-κB cooperate to regulate the uPA/uPAR system in cancer cells. Int. J. Cancer (2011) 128(6): 1280-1292

- Bougatef F et al. EMMPRIN Promotes Melanoma Cells Malignant Properties through a HIF-2alpha Mediated Up-Regulation of VEGF-Receptor-2. PLoS One (2010) 5(8): e12265

- Paule B et al. Soluble Isoforms of Vascular Endothelial Growth Factor Are Predictors of Response to Sunitinib in Metastatic Renal Cell Carcinomas. PLoS One (2010) 5(5): e10715

- Ma L et al. Antisense Inhibition of Amphiregulin Expression Reduces EGFR Phosphorylation in Transformed Human Breast Epithelial Cells. Anticancer Res. (2010) 30(6): 2101-2106

- Bougatef F et al. EMMPRIN promotes angiogenesis through hypoxia-inducible factor-2-mediated regulation of soluble VEGF isoforms and their receptor VEGFR-2. Blood (2009) 114(27): 5547-5556