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MITOCHONDRIAL GENES LIST FOR RESEARCH AND DIAGNOSTICS

Discover a comprehensive mitochondrial genes list curated for researchers exploring mitochondrial function, energy metabolism, and disease mechanisms. This resource includes essential genes involved in oxidative phosphorylation, apoptosis, and stress response, providing reliable targets for gene expression profiling and biomarker studies.

Whether you are studying mitochondrial dysfunction, identifying biomarkers, or developing diagnostic assays, this guide offers scientifically validated gene targets to accelerate your research.

AnyGenes qPCR Mitochondrial genes list for expression profiling and biomarker discovery

Why choose AnyGenes® qPCR arrays for mitochondrial genes research?

AnyGenes® offers advanced qPCR arrays for precise mitochondrial gene expression and function analysis. Our curated mitochondrial gene panel ensures reproducibility and reliability, enabling researchers to uncover novel insights into health and disease.

  • Precise detection: analyze essential mitochondrial genes linked to OXPHOS, mitochondrial biogenesis, and apoptosis with validated qPCR arrays.
  • Mitochondrial health: analyze gene expression related to neurodegenerative diseases, cardiovascular conditions, and metabolic disorders.
  • Functional insights: investigate mitochondrial dynamics and responses under various stress conditions, including oxidative stress and nutrient deprivation.

Our qPCR arrays offer high precision and reproducibility, helping you explore mitochondrial functions efficiently

Illustration of human mitochondrial genes list highlighting mtDNA structure and function.
Schematic of human mtDNA and basic steps of mtRNA metabolism

WHAT IS MITOCHONDRIAL GENES LIST?

A mitochondrial genes list is a reference set of genes directly linked to the structure and function of mitochondria. These genes play critical roles in :

  • Energy metabolism (OXPHOS, ATP production).
  • Cell survival and aging pathways.
  • Mitochondrial dynamics (fusion and fission).
  • Metabolic and degenerative disorders.

STRUCTURE OF HUMAN MITOCHONDRIA

Mitochondria are double-membraned organelles responsible for cellular energy production. Key components include:

  1. Outer membrane: smooth and permeable, separating the mitochondrion from the cytoplasm.
  2. Inner membrane: folded into cristae, houses the electron transport chain and ATP synthase.
  3. Intermembrane space: contains enzymes involved in oxidative phosphorylation.
  4. Matrix: includes Krebs cycle enzymes, mitochondrial DNA (mtDNA), and ribosomes.
  5. Mitochondrial DNA (mtDNA): Encodes proteins critical for mitochondrial function and regulation.

OUR CURATED MITOCHONDRIAL GENES LIST

At AnyGenes®, we deliver a scientifically validated mitochondrial genes list, directly integrated into our SignArrays® qPCR panels for accurate and reproducible profiling.

Examples of genes included (by complex or function):

  • Complex I: MT-ND1, MT-ND2, MT-ND3, MT-ND4, MT-ND4L, MT-ND5, MT-ND6….
  • Complex II: SDHA, SDHB, SDHC, SDHD
  • Complex III: UQCRC1, UQCRC2, UQCRFS1, UQCR10, UQCR11, UQCRB, UQCRH, UQCRQ, CYC1, MT-CYB
  • Complex IV: MT-CO1, MT-CO2, MT-CO3…
  • Complex V: ATP5F1A, ATP5F1B, ATP5F1C, MT-ATP6, MT-ATP8…
  • Regulation & maintenance: MRPL12, MTERF1, MTRES1…

Access the complete mitochondrial genes table below to accelerate your research.

HOW TO USE OUR MITOCHONDRIAL GENES LIST?

  • Perform gene expression profiling using AnyGenes® SignArrays® qPCR arrays.
  • Biomarker discovery for mitochondrial dysfunction
  • Drug response studies in metabolic and degenerative diseases.
  • Routine research in cell and molecular biology.

FREQUENTLY ASKED QUESTIONS

Key mitochondrial genes include both nuclear-encoded and mtDNA-encoded genes. They regulate oxidative phosphorylation, ATP production, mitochondrial DNA replication, and cellular stress responses. Examples include MT-ND1, MT-CO1, and nuclear genes like POLG and TFAM.

Using AnyGenes® qPCR arrays, you can study expression levels of mitochondrial genes under various experimental conditions, including stress, metabolic changes, or disease states.

Yes. Mitochondrial genes are often used as biomarkers to study mitochondrial dysfunction in diseases such as neurodegenerative disorders, diabetes, and cancer.

The human mitochondrial genome encodes 37 genes: 13 protein-coding genes, 22 tRNAs, and 2 rRNAs. Most other mitochondrial proteins are encoded by nuclear DNA and imported into mitochondria.

You can explore our curated list of mitochondrial biomarkers in the table below to check if they match your research needs. If your targets are not included, you can customize your own SignArrays® by downloading and completing our Personalized SignArrays® information file. Send it to  [email protected]  to get started on your project.

  1. Kotrys AV, Szczesny RJ. Mitochondrial Gene Expression and Beyond-Novel Aspects of Cellular Physiology. Cells (2019);9(1):17.
  2. Park D, Lee S, Min KT. Techniques for investigating mitochondrial gene expression. BMB Rep. (2020);53(1):3-9.
  3. Russell OM et al. Mitochondrial Diseases: Hope for the Future. Cell. (2020);181(1):168-188.
  4. Dard L, et al. Mitochondrial functions and rare diseases. Mol Aspects Med. (2020);71:100842.
  5. Habbane M, et al. Human Mitochondrial DNA: Particularities and Diseases. Biomedicines. (2021); 9(10): 1364.

HUMAN MITOCHONDRIA BIOMARKER LIST FOR RESEARCH AND DIAGNOSTICS

Customize your own signaling pathways (SignArrays®) with the factors of your choice!
Simply download and complete our Personalized SignArrays® information file and send it at [email protected] to get started on your project.

You can check the biomarker list included in this pathway, see below:

Looking for more answers? Visit our Help & FAQ section to find detailed informations about our products, services, and technical support.

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