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The EGF-PDGF signaling pathway is a complex network of molecular interactions that play a vital role in regulating various cellular processes. Epidermal Growth Factor (EGF) and Platelet-Derived Growth Factor (PDGF) are critical regulators of cell growth, differentiation and survival.
AnyGenes offers advanced SignArrays® designed for the high-throughput analysis of key components withing the EGF-PDGF pathways.These customizable qPCR arrays provide researchers with the tools to study these pathways in detail, contributing to breakthroughs in cancer research, regenerative medicine and targeted therapies.
Discover our advanced qPCR arrays for EGF-PDGF Signaling Pathway research.
The EGF-PDGF pathways play a crucial role in regulating cell growth, survival, migration, embryonic development, tissue repair and angiogenesis. However, when these pathways are dysregulated, they can contribute to various diseases including cancer, cardiovascular conditions, atherosclerosis, and fibrosis.
Targeting the EGF-PDGF pathway represents a promising strategy for cancer treatment. Inhibitors that block these pathways are being explored for their potential to reduce tumor growth and improve patient outcomes.
Understanding the interplay between these growth factors can lead to more effective combination therapies that disrupt multiple signaling routes involved in cancer progression.
Scientific data is only as powerful as the analysis behind it.
AnyGenes® provides a dedicated data analysis tool specifically developed for SignArrays® pathway panels.
What does it allow you to do?
Developed on Excel (compatible with 2007+), the software is user-friendly and requires no advanced bioinformatics skills.
Customize your own signaling pathways (SignArrays®) with the factors of your choice!
Simply download and complete our Personalized SignArrays® information file
and send it at
[email protected]
to initiate your project.
| Signaling Pathways | Product ref | Informations |
|---|---|---|
EGF-PDGF Signaling Pathway | EGF1H1 |
| Signaling Pathways | Product ref | Informations |
|---|---|---|
EGF-PDGF Signaling Pathway | EGF1M1 |
| Signaling Pathways | Product ref | Informations |
|---|---|---|
EGF-PDGF Signaling Pathway | ******* |
Biomarker list in progress. |
| Signaling Pathways | Product ref | Informations |
|---|---|---|
EGF-PDGF Signaling Pathway | ******* |
Biomarker list in progress. |
Looking for more answers? Visit our Help & FAQ section to find detailed informations about our products, services, and technical support.
1. Sun Z, et al. Predominant control of PDGF/PDGF receptor signaling in the migration and proliferation of human adipose‑derived stem cells under culture conditions with a combination of growth factors. Exp Ther Med. (2024)21;27(4):156.
2. Pandey P, et al. New insights about the PDGF/PDGFR signaling pathway as a promising target to develop cancer therapeutic strategies. Biomed Pharmacother. (2023):161:114491.
3. Moench R, et al. Platelet-derived growth factor (PDGF) cross-signaling via non-corresponding receptors indicates bypassed signaling in colorectal cancer. Oncotarget. (2022)19;13:1140-1152.
4. Bernal-Mizrachi E, et al. Human β-cell proliferation and intracellular signaling part 2: still driving in the dark without a road map. Diabetes. (2014)13;63(3):819–831.
5. Heldin CH. Targeting the PDGF signaling pathway in tumor treatment. Cell Commun Signal. (2013)20;11:97.